As the secrets of DNA unravel, humans are increasingly able to control and even redirect their genes, changing their personalities and destinies. Gigi and Marlene work at a biotech company, developing medicine to suppress specific genes and their effects on the human body. The two girls are roommates, united by a common gene, the “clean-freak” gene, that makes them allergic to dirty, dusty, or smelly environments. After both girls have their own unsatisfied relationships, they decide that it’s time to make some changes and… compromises. Gigi and Marlene take a drug to suppress their “clean-freak” gene. As their exterior lives grow ever messier, will their interior lives reach happiness?